Intermittent Claudication and Asymptomatic Peripheral Arterial Disease

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Management of peripheral arterial disease and intermittent claudication.

BACKGROUND Peripheral arterial disease (PAD) is the chronic obstruction of the arteries supplying the lower extremities. The most common symptom is intermittent claudication resulting in aching pain, numbness, weakness, or fatigue in the muscle groups of the lower extremities. METHODS Using the key words "peripheral arterial disease," "intermittent claudication," "atherosclerosis," and "cardi...

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Asymptomatic peripheral arterial disease is associated with more adverse lower extremity characteristics than intermittent claudication.

BACKGROUND This study assessed functional performance, calf muscle characteristics, peripheral nerve function, and quality of life in asymptomatic persons with peripheral arterial disease (PAD). METHODS AND RESULTS PAD participants (n=465) had an ankle brachial index <0.90. Non-PAD participants (n=292) had an ankle brachial index of 0.90 to 1.30. PAD participants were categorized into leg sym...

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Factors predicting walking intolerance in patients with peripheral arterial disease and intermittent claudication.

OBJECTIVE To determine which physiological variables conduce to walking intolerance in patients with peripheral arterial disease (PAD). DESIGN The physiological response to a graded treadmill exercise test (GTT) in patients with PAD was characterised. SETTING Patients were recruited from the Department of Vascular Surgery, Groote Schuur Hospital, Cape Town. SUBJECTS Thirty-one patients di...

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Exertional leg symptoms other than intermittent claudication are common in peripheral arterial disease.

BACKGROUND Epidemiological data show that most community-dwelling men and women with lower-extremity peripheral arterial disease (PAD) do not have typical symptoms of intermittent claudication. We compared the prevalence of intermittent claudication, leg symptoms other than intermittent claudication, and absence of exertional leg symptoms between patients with PAD identified from a blood flow l...

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Pathophysiology of Intermittent Claudication in Peripheral Artery Disease.

Peripheral artery disease (PAD) affects more than 200 million adults worldwide. Patients with lower extremity PAD have a heightened risk for cardiovascular events because of the systemic nature of atherosclerosis, and benefit from treatment with risk factor-modifying therapies. Limb symptoms in PAD include intermittent claudication and diminished walking ability. Arterial obstruction from ather...

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ژورنال

عنوان ژورنال: Deutsches Aerzteblatt Online

سال: 2020

ISSN: 1866-0452

DOI: 10.3238/arztebl.2020.0188